The flagship Personalized, Real-Time Health Impact of Climate Change and Pollution is excited to announce the release of their latest publication: Advances in Organ-on-a-Chip Technology to Examine the Impact of Air Pollutants on Epithelial Barrier Tissues. This review explores the latest breakthroughs in organ-on-a-chip models and how they contribute to our ability to study the effects of air pollutants on key barrier tissues. The review offers timely insights for those interested in the evolving intersection of environmental health and bioengineering.